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Tool for analysing viral diversity from HTS

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This programs has been developed as a result of working with virologist and microbiologist who are interested in understand intra-host diversity of viruses and bacteria and their evolution on a micro-evolutionary scale. A lot of tools exist that determine the frequency of mutations (SNPs, indels) from SAM files but these have primarily been developed for diploid model organisms. DiversiTools on the other hand focuses on determining mutations from a population of haploid organisms. The large amount of sequence data provided by HTS (High-throughput sequencing) enables us to study virus and bacterial populations beyond the consensus.

To learn to use DiversiTools have a run through the different tutorials:

Papers using DiversiTools (previously btctools)

Authors and Contributors

This project is a collaboration between @rjorton and @josephhughes to enable virologists and microbiologists to understand the intra-host variation from their high-throughput reads.