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Beyond the consensus HTS (High-throughput sequencing) tools

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This program has been developed as a result of working with virologists and microbiologists, who are interested in understanding the intra-host diversity of viruses and bacteria and their micro-evolution. Many tools exist that determine the frequency of mutations (SNPs, indels) from SAM files but these have primarily been developed for diploid model organisms. On the other hand, DiversiTools focuses on determining mutations from a population of haploid organisms.

You can learn how to use DiversiTools by following the different tutorials:

Authors and Contributors

This project is a collaboration between @rjorton and @josephhughes to enable virologists and microbiologists to understand the intra-host variation from their high-throughput reads.